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Nexgard Spectra



Nexgard Spectra

active ingredients included in the preparation provide its wide spectrum of antiparasitic action against ectoparasites and nematodes parasitizing in dogs:fleas (Ctenocephalides felis, Ctenocephalides can is); ixodid ticks (Dermacentor variabilis, Dermacentor reticulatus, Rhipicephalus sanguineus, Ixodes scapularis, Ixodes ricinus, Ixodes holocyclus, Haemaphysalis longicornis, Amblyomma americanum);

  • gastrointestinal nematodes (Toxocara canis, Toxascaris leonina, Ancylostoma caninum, Ancylostoma braziliense, Trichuris vulpis);
  • larvae of dirofilariae ( Dirofilaria immitis ).

Frontline Nexgard Spectra contains two active ingredients: afoxolaner and milbemycin oxime.

Afoxolaner is an insectoacaricide from the group of isoxazolines, known as the active ingredient of Frontline

The studies performed have demonstrated similar pharmacokinetics of afoxolaner molecules in combination with milbemycin oxime.

Thus, it was confirmed that the effectiveness against fleas and ticks oare at the same level.

The drug takes effect within 30 minutes after application.

The parasites die within 6 hours throughout the month.

The high speed of action prevents fleas from laying eggs, interrupting their development cycle, which makes it possible to effectively use  in the treatment of flea allergic dermatitis.

The action of afoxolaner against ixodid ticks begins within 4 hours after application.

Within a month, Frontlinetroys ticks within 24 hours, which is enough to prevent vector diseases transmitted by ticks: studies have shown 100% protection of dogs against infection with babesiosis and borreliosis.

Afoxolaner is effective for the treatment of generalized demodicosis and sarcoptic mange in dogs.

The effectiveness of therapy for these diseases was more than 99% one month after the start of treatment.

Due to the fact that afoxolaner is prescribed once a month and the dog is regularly seen by the veterinarian to assess the results of treatment, the cost of treatment is optimized.

The addition of milbemycin oxime made it possible to expand the spectrum of the drug’s action, adding to the effectiveness of afoxolaner the effect on helminths.

Frontline provides 100% prevention of dirofilariasis (action on microfilariae), and is also highly effective against other nematodes: ascaris, whipworms, hookworms.

Now only one tablet is required to protect your dog from ticks, fleas and effectively kill worms.

Frontline Nexgard Spectra is a safe drug, as evidenced by a study of the drug with a five-fold overdose on more than 700 dogs of various breeds, including collie dogs.

An important feature of Frontline Nexgard Spectra is the form of application.

Nexgard Spectra is a chewable tablet with a high palatability, which makes the administration of the drug simple and convenient for both the owner and the veterinarian.

The advantage is the possibility of using Frontline Nexgard Spectra with or without feed.

Nexgard Spectra – really convenient:

  • For dogs that are frequently bathed or washed with shampoo
  • For dogs with skin conditions
  • For wearers who find it uncomfortable to use drugs in the form of collars or drops
  • Can be administered with or without food
  • One treatment for both external and internal parasites
  • Fast protection – already in 2 – 4 hours


Corn starch 25%, soy protein flour 20%, beef stew aroma and flavor additive 20%, K30 povidone 2.7%, macrogol 400 – 7.1%, macrogol 4000 – 6.3%, macrogol 15 hydroxystearate – 3.1%, glycerol – 10%, medium-chain triglyceride – 3.1%, potassium sorbate – 0.3%.


Afoxolaner – 1.87% (in 1 tablet 9.4 mg)
Milbemycin oxime – 0.38% (1 tablet 1.9 mg)


Dog weight (kg) Tablet weight (g) Dose of active ingredients (mg / tablet)
afoxolaner milbemycin oxime
from 3.5 to 7.5 1.0 18.8 3.8
from 7.5 to 15 2.0 37.5 7.5
from 15 to 30 4.0 75.0 15.0
from 30 to 60 8.0 150.0 30.0


Application and dosage:

Dogs individually orally once in a minimum dose of 2.5 mg of afoxolaner and 0.5 mg of milbemycin oxime per 1 kg of animal weight.

Repeated treatments in the season of greatest activity of ectoparasites are carried out monthly.


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